Related Experiment Video
Updated: Aug 9, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Time to exhaustion during severe intensity running: response following a single bout of interval training
1Cheltenham and Gloucester College of Higher Education, Leisure and Sport Research Unit, Francis Close Hall, Swindon Rd, Cheltenham, Gloucestershire, GL50 4AZ, UK. djames@chelt.ac.uk
Abstract:
The primary aim of this study was to examine any change in performance caused by a fatiguing interval training session (TS). A secondary aim of this study was to examine the change in oxygen uptake (VO(2)) during moderate and severe intensity running, and the relationship with the change in performance. Seven male runners [mean age 24 (SD 6) years, height 1.79 (SD 0.06) m, body mass 67.9 (SD 7.6) kg, maximal oxygen uptake (VO(2max)) 4.14 (SD 0.49) l. min(-1)] were studied. The VO(2) during moderate and severe intensity running and running performance were studied immediately prior to, 1 h following, and 72 h following TS. The TS was performed on a treadmill, and consisted of six bouts of 800 m at 1 km. h(-1) below the velocity at VO(2max) (v(V)O(2max)), with 3-min rest intervals. Performance was also assessed at 1 km. h(-1) below v(V)O(2max), in the form of time to exhaustion (t(lim)). The VO(2) and heart rate (f(c)) were assessed both during the severe intensity performance trial, and the moderate intensity run at 50% v(V)O(2max). Whilst a significant change was observed in running performance and the VO(2) during both moderate and severe intensity running prior to and following TS, no relationship was observed between the magnitude of change in these variables. At 1 h following TS, t(lim) had decreased by 24%, VO(2) during moderate intensity running had increased by 2%, and the difference in VO(2) between 2 min 45 s and the end of severe intensity running had increased by 91% compared with values recorded prior to TS. At 1 h following TS, f(c) had also increased significantly during moderate intensity running by 5% compared to the value recorded prior to TS. These findings demonstrated that TS resulted in a reduction in performance, and that the relationship between running performance and VO(2) during running may be altered under conditions of prolonged fatigue.
Related Concept Videos
Muscle Recovery and Fatigue
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

