Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Performance evaluation and planning for patient-based quality control procedures.

J J Ye1, S C Ingels, C A Parvin

  • 1Department of Pathology, Washington University School of Medicine, St Louis, MO 63110, USA.

American Journal of Clinical Pathology
|February 9, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Research advances on hepatic encephalopathy following transjugular intrahepatic portosystemic shunt].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2026
Same author

[Efficacy and safety of PD-1 inhibitors combined with chemotherapy for the treatment of local recurrence at the primary tumor site of ESCC following definitive chemoradiotherapy or radiotherapy].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2025
Same author

[A case of Fabry disease with cardiac injury as the main clinical manifestation].

Zhonghua xin xue guan bing za zhi·2024
Same author

[Investigation and analysis on the detection of IgG antibodies against the rubella virus among rural childbearing-age women in preconception period in Yunnan Province from 2013 to 2019].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2024
Same author

[Analysis of prognostic factors of extranodal NK/T-cell lymphoma treated with pegaspargase/L-asparaginase: a multicenter retrospective study].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2023
Same author

[Clinical prognostic analysis of 124 adult patients with hemophagocytic lymphohistiocytosis: a multicenter retrospective study of the Huaihai Lymphoma Working Group].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2021

The average number of patient samples that contain unacceptable analytic error (ANPTE) offers a new way to assess quality control (QC) performance. This metric reveals different conclusions about QC procedures compared to traditional methods.

Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Quality Control

Background:

  • Routine quality control (QC) is essential for ensuring laboratory test accuracy.
  • Traditional QC performance measures may not fully capture the impact of testing intervals on patient safety.
  • A novel performance metric, the average number of patient samples that contain unacceptable analytic error (ANPTE), has been proposed.

Purpose of the Study:

  • To evaluate the suitability of ANPTE for assessing patient-based QC procedures.
  • To investigate the impact of the time interval between QC tests on QC performance using ANPTE.
  • To analyze the influence of averaging patient results and truncation limit width on an average of normals QC procedure.

Main Methods:

  • Utilized computer simulations with actual patient result distributions to estimate ANPTE.

Related Experiment Videos

  • Applied the ANPTE metric to analyze the effects of QC testing frequency.
  • Examined the impact of the number of averaged patient results and truncation limit width on QC performance.

    • Main Results:

    • ANPTE is effective for evaluating patient-based QC procedures.
    • The frequency of QC testing significantly impacts QC performance as measured by ANPTE.
    • Findings on the effects of truncation limits and patient result averaging differ from previous studies using probability of error detection.

    Conclusions:

    • ANPTE provides a more comprehensive assessment of QC performance, particularly concerning patient risk.
    • The interval between QC tests is a critical factor influencing the reliability of laboratory diagnostics.
    • This study highlights the limitations of traditional QC metrics and advocates for ANPTE in evaluating modern QC strategies.