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Updated: Jul 19, 2026

Construction and Characterization of a Novel Vocal Fold Bioreactor
Published on: August 1, 2014
Viscoaugmentation as a treatment for leakage around the Provox 2 voice rehabilitation system
D A Luff1, S Izzat, W T Farrington
1Department of Otolaryngology-Head and Neck Surgery, Manchester Royal Infirmary, UK.
Abstract:
Tracheo-oesophageal puncture for voice restoration is a well-established technique post-laryngectomy. A number of complications can occur with the creation of a tracheo-oesophageal fistula (TOF) and in the subsequent management of the patient with an indwelling voice rehabilitation system. This article is the first to report the use of Hylaform, a colourless viscoelastic gel, to treat an intractable case of leakage around a Provox 2 voice prosthesis. The procedure which required no anaesthesia resulted in no further leak around the valve to the present day, now more than four weeks post-viscoaugmentation.
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