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Updated: Jul 17, 2026

Isolation, Culture, and Genetic Engineering of Mammalian Primary Pigment Epithelial Cells for Non-Viral Gene Therapy
Published on: February 26, 2021
[A study of genetic character and foreign OMT/PGH gene integration in transgenic swine]
Abstract:
By using isotopic and non-isotopic in situ hybridization on chromosomes, the locus on chromosomes of foreign OMT/PGH gene was analyzed in eight transgenic pigs (G0, G1,G2 and G3). The research result is as follows: (1) The foreign genes could integrated on chromosomes of pig and the foreign integrated randomly; (2) the foreign genes integrated on chromosomes were transmissible through generations; (3) the locus on chromosomes of foreign gene was relatively stable in alternation of generations in transgenic swine.
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