Compliance with prescription filling in the pediatric emergency department

D Matsui1, G I Joubert, S Dykxhoorn

  • 1Department of Pediatrics, Children's Hospital of Western Ontario, University of Western Ontario, London, Canada. dmatsui@julian.uwo.ca

Insights

Most pediatric emergency department prescriptions are filled, with 92.7% compliance. Key reasons for non-adherence include perceived medication necessity and financial constraints, highlighting areas for improved patient communication.

Area of Science:

  • Pediatric Emergency Medicine
  • Health Services Research
  • Pharmacoeconomics

Background:

  • Prescription non-adherence is a significant challenge in pediatric healthcare.
  • Understanding reasons for non-adherence is crucial for optimizing treatment outcomes.

Purpose of the Study:

  • To determine the rate of prescription filling compliance in a pediatric emergency department.
  • To identify parental reasons for not filling prescribed medications.

Main Methods:

  • A standardized telephone questionnaire was used for follow-up.
  • Compliance was defined as filling prescriptions on the same or next day.
  • The study included pediatric patients discharged from a tertiary care hospital's emergency department.

Main Results:

  • Follow-up was completed for 1014 children (83% of 1222).
  • Prescription filling compliance was high at 92.7%.
  • Primary reasons for non-filling included perceived medication necessity (27%), financial issues (6.8%), and time constraints (6.8%).

Conclusions:

  • The rate of prescription non-filling in pediatric emergency departments is at least 7%.
  • Dissatisfaction with medical explanations and treatment instructions was linked to non-compliance.
  • Findings suggest opportunities to improve patient education and communication to enhance adherence.
Abstract

Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...