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Crystallization and preliminary analysis of bovine adenosine deaminase
T Kinoshita1, N Nishio, A Sato
1Basic Research Laboratories, Fujisawa Pharmaceutical Co. Ltd, 1-6, Kashima 2-Chome, Yodogawa-ku, Osaka 532-8514, Japan. takayoshi_kinoshita@po.fujisawa.co.jp
Acta Crystallographica. Section D, Biological Crystallography
|February 10, 2000
Abstract:
Adenosine deaminase (ADA) from bovine intestine was crystallized with purine riboside by vapour diffusion using ammonium sulfate as precipitant. The crystals are tetragonal and have unit-cell parameters a = b = 80.03, c = 141.68 A. They belong to space group P4(1)2(1)2 or P4(3)2(1)2 and diffract to at least 2.0 A resolution. The structure is being solved by molecular replacement.