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Candidiasis

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

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Related Experiment Video

Updated: Jul 1, 2026

Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening

Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening

Published on: July 18, 2012

[Candida in biological human samples].

H Vargas-Montiel¹, N Vargas-Caminos, M Molero

¹Escuela de Medicina, Facultad de Medicina, Universidad del Zulia, Venezuela.

Investigacion Clinica

|February 10, 2000

Summary

This summary is machine-generated.

Candida infections are increasing, with Candida species other than C. albicans becoming more prevalent. Early diagnosis using microscopy and cultures is crucial for effective treatment of candidiasis.

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Area of Science:

Medical Mycology
Infectious Diseases
Clinical Microbiology

Background:

Rising incidence of Candida infections globally.
Immunosuppression and non-albicans Candida species are key prognostic factors.
Candidiasis is a common hospital-acquired mycosis.

Purpose of the Study:

To determine the prevalence of Candida albicans and other Candida species in patients at Hospital Universitario de Maracaibo.
To correlate yeast identification with clinical presentation and sample type.

Main Methods:

Analysis of 177 biological samples over two years (October 1996-October 1998).
Direct microscopic examination and fungal cultures for yeast isolation and identification.
Identification of blastoconidia and pseudohyphae for etiological diagnosis.

Main Results:

Candida species (58.75%) were more prevalent than Candida albicans (41.24%).
Blastoconidia and pseudohyphae were observed in 19.21% of samples.
Candida albicans was more frequent in intertrigo, sputum, and bronchial lavage; Candida species predominated in nail samples.

Conclusions:

Accurate etiological diagnosis of candidiasis requires both direct microscopy and culture methods.
Recognizing the prevalence of different Candida species is vital for patient management.
Subungual candidiasis in hospital staff poses a potential infection risk to inpatients.