Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New trends in insomnia management.

T Roth1

  • 1Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA. troth1@hfhs.org

Journal of Psychopharmacology (Oxford, England)
|February 10, 2000
PubMed
Summary

New hypnotics offer evolving insomnia treatment options. Further research is needed to assess their impact on daytime function, health, and costs, alongside sleep quality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

24&#x2003;Evaluation of an antibody-free approach to identifying faecal peptides for pregnancy detection in polar bears (<i>Ursus maritimus</i>).

Reproduction, fertility, and development·2022
Same author

Materials Imaging and Dynamics (MID) instrument at the European X-ray Free-Electron Laser Facility.

Journal of synchrotron radiation·2021
Same author

Efficacy of piperacillin in combination with novel β-lactamase inhibitor IID572 against β-lactamase-producing strains of Enterobacteriaceae and Staphylococcus aureus in murine neutropenic thigh infection models.

The Journal of antimicrobial chemotherapy·2020
Same author

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

The Journal of antimicrobial chemotherapy·2018
Same author

Pharmacokinetics and pharmacodynamics of the novel monobactam LYS228 in a neutropenic murine thigh model of infection.

The Journal of antimicrobial chemotherapy·2018
Same author

How representative are insomnia clinical trials?

Sleep medicine·2018

Area of Science:

  • Pharmacology
  • Sleep Medicine
  • Psychiatry

Background:

  • Insomnia management is advancing with new non-benzodiazepine hypnotics.
  • Insomnia significantly impacts daytime function, long-term health, and socioeconomic status.
  • Epidemiological data links insomnia to increased absenteeism and healthcare expenses, partly due to comorbid depression.

Purpose of the Study:

  • To evaluate the broader benefits of hypnotics beyond sleep.
  • To determine if hypnotics improve daytime functioning, health, and socioeconomic parameters.
  • To explore the necessity of additional outcome measures like quality of life and healthcare costs.

Main Methods:

  • Review of pharmacological activity and receptor differences of new hypnotics.
  • Analysis of epidemiological data on insomnia's impact.
  • Investigation into alternative prescribing patterns and their consequences.

Main Results:

  • Non-benzodiazepine hypnotics present diverse pharmacological profiles.
  • Long-term hypnotic use is common, necessitating alternative administration strategies.
  • Data on chronic efficacy and safety of long-term hypnotic use remains limited.

Conclusions:

  • Further research is required to ascertain the full patient benefits of hypnotics.
  • Alternative administration schedules (intermittent, 'as required') are under investigation.
  • Careful consideration of abuse liability and efficacy perception is crucial for appropriate hypnotic use.

Related Experiment Videos