[Peripheral giant cell granuloma of the jaw. Study of 173 cases]

The authors studied G.C.P.G. in a series of 173 patients amongst 894 with epulis type tumours. The highest occurrence rate of G.C.P.G. was found during the period of mixed dentition. Whilst in childhood G.C.P.G. was commoner in boys than girls, after the age of 16 the number of women affected was twice that of men. G.C.P.G. occurs more frequently in the mandible than the maxilla and more often in the premolar-molar region than the incisor-canine region. Osteolysis of the alveolar edge was more marked than in other forms of epulis and in a smaller number of cases osteogenic forms of G.C.P.G. were found with the formation of a substantial amount of reactive bone. From a histopathological standpoint, a connective-tissue/vascular stroma with giant cells and developing in relation with the capillary endothelium, and of similar appearance to G.C.C.G., is noted.