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[Transrectal specimens in recurrent rectal cancer].

S G Larsen¹, J N Wiiu, K E Giercksky

¹Avdeling for kirurgisk onkologi, Det Norske Radiumhospital, Oslo.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke

|February 11, 2000

Summary

Transrectal digitally guided fine needle aspiration cytology (FNAC) offers a sensitive and cost-effective method for diagnosing recurrent rectal cancer. This technique aids in early detection, guiding timely treatment for improved patient outcomes.

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Area of Science:

Oncology
Gastroenterology
Surgical Pathology

Background:

Rectal cancer recurrence commonly occurs in the pelvis, often detectable before mucosal penetration.
Current diagnostic methods may delay detection of extraluminal recurrences.

Observation:

Transrectal digitally guided fine needle aspiration cytology (FNAC) was evaluated for diagnosing rectal cancer recurrence.
Biopsies were taken through intact mucosa or from intraluminal tumors.

Findings:

FNAC demonstrated a higher sensitivity (0.88) compared to fine needle core biopsy (FNCB) (0.68) (p < 0.005).
No false positive diagnoses were reported.
The procedure is simple, cost-effective, safe, and has a low complication rate.

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Implications:

Digitally guided transrectal biopsy provides an adequate early morphological diagnosis, potentially avoiding more expensive imaging-guided biopsies.
Surgical treatment for locally recurrent rectal cancer, combined with radiation therapy, can improve quality of life, prolong survival, and offer a chance of cure.