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[Encrusted alkaline cystitis and malacoplakia].

L A Fariña Pérez1, P Menéndez, A Astudillo

  • 1Servicio de Urología, Anatomía Patológica, Hospital Monte Naranco.

Actas Urologicas Espanolas
|February 12, 2000
PubMed
Summary
This summary is machine-generated.

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Urinary tract infections from urea-splitting bacteria can cause alkaline encrusted cystitis, a rare bladder condition. This case highlights a link between this condition and malakoplakia, suggesting a shared cause.

Area of Science:

  • Urology
  • Microbiology
  • Pathology

Background:

  • Urinary infections by urea-splitting bacteria elevate urinary pH, promoting calcium salt and struvite crystal precipitation.
  • This precipitation can lead to alkaline encrusted cystitis, a rare bladder condition, particularly on pre-existing bladder lesions or chronic inflammation.

Observation:

  • A rare case of alkaline encrusted cystitis in a 69-year-old male is presented.
  • The patient's urine culture showed growth of Corynebacterium urealyticum.
  • Endoscopic excision of the encrusted area revealed foci of malakoplakia.

Findings:

  • This case represents the third reported instance of alkaline encrusted cystitis associated with malakoplakia.
  • Both conditions share similar clinical manifestations.

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Implications:

  • The findings suggest a potential common etiopathogenesis between alkaline encrusted cystitis and malakoplakia.
  • Further research into this shared pathway could improve understanding and treatment of these rare conditions.