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A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Intimal-medial thickness of the common carotid arteries and lower limbs atherosclerosis in the elderly
F Mattace Raso1, M Rosato, A Talerico
1Chair of Geriatric Medicine, University of Catanzaro.
Insights
Intimal-media thickness of the common carotid arteries is linked to lower limb atherosclerosis in elderly patients. This measurement can help identify individuals at risk for cardiovascular diseases.
Area of Science:
- Vascular Medicine
- Cardiology
- Geriatrics
Background:
- Investigating the link between carotid artery intimal-media thickness (IMT) and lower limb atherosclerosis in the elderly.
- Examining the role of cardiovascular risk factors in this association.
Purpose of the Study:
- To determine if increased common carotid artery IMT is associated with lower limb atherosclerosis.
- To assess the utility of IMT as a marker for generalized atherosclerosis and cardiovascular risk in elderly individuals.
Main Methods:
- B-mode ultrasound was used to measure common carotid artery IMT in 80 elderly subjects.
- Lower limb atherosclerosis was identified by intermittent claudication and/or ankle-arm index < 0.9.
- Linear regression analysis evaluated the relationship between IMT and lower limb atherosclerosis, considering cardiovascular risk factors.
Main Results:
- A statistically significant association was found between increased common carotid artery IMT and lower limb atherosclerosis.
- The majority of subjects (80%) had one or more cardiovascular risk factors.
- The study highlights the prevalence of risk factors in this elderly cohort.
Conclusions:
- Common carotid artery IMT serves as a marker for generalized atherosclerosis.
- IMT measurement can aid in identifying elderly individuals at risk for cardiovascular diseases, even in early stages.
- This finding supports the use of IMT in cardiovascular risk assessment.
Background:
In the present study, the authors consider the possible association between intimal-media thickness of the common carotid arteries and lower limb atherosclerosis, in a group of elderly patients; the authors also consider the presence of cardiovascular risk factors.
Methods:
B-mode ultrasound measurement of the intimal-media thickness of the common carotid arteries was performed on 80 subjects. Lower limbs atherosclerosis was defined as the presence of intermittens claudicatio and/or ankle-arm index < 0.9. Baseline clinic examination and blood tests were performed in all subjects to consider the presence of cardiovascular risk factors. Linear regression analysis was used to assess the linear relationship between intimal-media thickness of the common carotid arteries and lower limb atherosclerosis.
Results:
Linear regression analysis showed a statistical association between increased values of intimal-media thickness of the common carotid arteries and lower limb atherosclerosis. Sixty-four (80%) subjects presented one or more associated cardiovascular risk factors.
Conclusions:
The results of the the present study confirm that intimal-media thickness of the common carotid arteries is a marker for the identification of generalized atherosclerosis and may be useful for the identification of subjects, even at early stages, at risk of cardiovascular diseases.
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