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Updated: Aug 18, 2026

LabVIEW-operated Novel Nanoliter Osmometer for Ice Binding Protein Investigations
Published on: February 4, 2013
[Ni]
1Institut für Anorganische Chemie Universität Erlangen-Nürnberg Egerlandstrasse 1, 91058 Erlangen (Germany).
Abstract:
How do [NiFe] hydrogenases activate H(2)? Hydrogenases are key enzymes in the biological hydrogen and energy metabolism; the mechanism of H(2) activation, however, is unclarified. In particular, the oxidation states of the metals involved are discussed controversially. The title complex demonstrates that a distorted diamagnetic Ni(II) center and thiolate donors are sufficient (see picture) to catalyze the key reaction of hydrogenases, the H(2) heterolysis.
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