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Phospholipase A(2) enzymes: structural diversity in lipid messenger metabolism
1European Molecular Biology Laboratory, Grenoble, 38000, France. dessen@embl-grenoble.fr.
Structure (London, England : 1993)
|February 16, 2000
Abstract:
The phospholipases A(2) (PLA(2)s) are a large family of enzymes with varied lipidic products which are involved in numerous signal transduction pathways. The structural and functional characterization of several PLA(2)s have revealed the various mechanisms used by these enzymes to ingeniously manipulate the phospholipidic metabolic machinery.