The judicious use of antibiotic agents in common childhood respiratory illness
1Departments of Infection Control and Occupational Health, Children's Hospital of Philadelphia, Pennsylvania 19104, USA.
Insights
Widespread antimicrobial use fuels bacterial resistance, especially when treating children's respiratory infections. This article guides judicious antimicrobial prescribing for common childhood illnesses to combat resistance.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pharmacology
Background:
- Antimicrobial resistance is a growing global health threat.
- Inappropriate antimicrobial use is common for pediatric respiratory tract infections.
- This contributes significantly to the development of resistant bacterial strains.
Purpose of the Study:
- To review the appropriate use of antimicrobial agents in pediatric respiratory illnesses.
- To provide guidance on judicious prescribing to mitigate antimicrobial resistance.
- To address common conditions including otitis media, sinusitis, pharyngitis, bronchitis, and the common cold.
Main Methods:
- Literature review of antimicrobial resistance patterns.
- Analysis of current treatment guidelines for pediatric respiratory infections.
- Discussion of evidence-based prescribing practices.
Main Results:
- Antimicrobial agents are frequently overprescribed for viral infections.
- Specific diagnostic criteria and treatment durations are essential for appropriate use.
- Judicious prescribing can significantly reduce unnecessary antimicrobial exposure.
Conclusions:
- Optimizing antimicrobial use in children is critical to curb resistance.
- Adherence to guidelines for common respiratory infections is paramount.
- Stewardship programs are vital for preserving antimicrobial efficacy.
Abstract:
Increased bacterial resistance is caused most frequently by the widespread use of antimicrobial agents. Antimicrobial agents are often used inappropriately to treat common respiratory illnesses in children. This article discusses the judicious use of antimicrobials in the common cold, otitis media, acute sinusitis, pharyngitis, and bronchitis.
Related Concept Videos
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Tonsillitis II: Management
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Microbiota of the Respiratory Tract
Mechanism of Antibiotic Resistance in MRSA


