Simple and efficient method for the detection of diethylenetriaminepentaacetic acid

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Study of Short Peptide Adsorption on Solution Dispersed Inorganic Nanoparticles Using Depletion Method
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Study of Short Peptide Adsorption on Solution Dispersed Inorganic Nanoparticles Using Depletion Method

Published on: April 11, 2020

C Weber1, M Michaelis, J U Vogel

  • 1Institut für Pharmazeutische Technologie, Biozentrum Niederursel, Johann Wolfgang Goethe-Universität, Frankfurt a.M., Germany.

Journal of Chromatography. B, Biomedical Sciences and Applications
|February 17, 2000
PubMed

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Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...