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Related Experiment Videos

Group differences in the relationship between apathy and depression.

R S Marin1, S Firinciogullari, R C Biedrzycki

  • 1Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.

The Journal of Nervous and Mental Disease
|April 1, 1994
PubMed
Summary
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Apathy and depression are distinct conditions, with their relationship varying across diagnoses like Alzheimer's disease and stroke. This supports differentiating apathy from depression in clinical settings.

Area of Science:

  • Gerontology
  • Neurology
  • Psychiatry

Background:

  • Apathy and depression are common in older adults, but their distinctness requires further investigation.
  • Understanding the relationship between apathy and depression is crucial for accurate diagnosis and treatment.

Purpose of the Study:

  • To evaluate the discriminability of apathy and depression.
  • To determine if the relationship between apathy and depression varies across different diagnostic groups.

Main Methods:

  • 123 subjects (mean age 72) were assessed using the Apathy Evaluation Scale and Hamilton Rating Scale for Depression.
  • Participants included healthy elderly controls, patients with left or right hemisphere stroke, probable Alzheimer's disease, and major depression.

Main Results:

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  • Elevated apathy without depression was most common in Alzheimer's disease and right hemisphere stroke.
  • In major depression, apathy often co-occurred with depression, but not always.
  • Significant positive correlations between apathy and depression were found in left hemisphere stroke, Alzheimer's disease, and major depression.

Conclusions:

  • The relationship between apathy and depression differs significantly across diagnostic groups.
  • These findings support the discriminability of apathy and depression as distinct clinical entities.