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Epstein-Barr virus: Co-opting B-cell memory and migration
1CRC Institute for Cancer Studies, MRC Centre for Immune Regulation, University of Birmingham, Edgbaston, B15 2TT, UK. A.B.Rickinson@bham.ac.uk
Current Biology : CB
|February 19, 2000
Abstract:
Epstein-Barr virus, a B-lymphotropic human herpesvirus, persists in vivo by entering the long-lived memory B-cell compartment. Work with genetically modified mice suggests that the viral latent membrane protein LMP1 might allow infected B cells to access the memory compartment by an unusual route.