Related Experiment Videos
Electrostatic steering of substrate to acetylcholinesterase: analysis of field fluctuations
S T Wlodek1, T Shen, J A McCammon
1National Center for Genome Resources, 1800-A Old Pecos Trail, Santa Fe, NM 87505, USA.
Biopolymers
|February 19, 2000
Abstract:
Based on previous molecular dynamics simulation results for acetylcholinesterase dimer, we calculate and analyse the electrostatic field fluctuations around the enzyme. The results show that dynamic features of the electrostatic field favor attraction of the positively-charged substrate. An Internet link to an animation of the results is also provided.