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Related Experiment Videos

Stereotactic radiosurgery for recurrent ependymoma.

S L Stafford1, B E Pollock, R L Foote

  • 1Division of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

Cancer
|February 19, 2000
PubMed
Summary
This summary is machine-generated.

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Stereotactic radiosurgery (SRS) offers effective local control for recurrent intracranial ependymomas, potentially improving patient survival. Further research into SRS as an initial treatment is recommended to reduce local failures.

Area of Science:

  • Neuro-oncology
  • Radiation Oncology

Background:

  • Recurrent intracranial ependymomas pose significant treatment challenges.
  • Evaluating the efficacy of stereotactic radiosurgery (SRS) for these challenging cases is crucial.

Purpose of the Study:

  • To assess local control, overall survival, and complications associated with SRS in patients with recurrent intracranial ependymomas.

Main Methods:

  • Stereotactic radiosurgery (SRS) was performed on 12 patients with 17 recurrent ependymoma tumors.
  • Patients had prior surgery and radiation; median SRS marginal dose was 18 Gy.

Main Results:

  • Median overall survival after SRS was 3.4 years.
  • Local control was achieved in 14 of 17 tumors (estimated 3-year control: 68%).

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  • Two patients experienced treatment-related complications.

    • Conclusions:

    • SRS demonstrates good local tumor control and may positively impact survival for recurrent intracranial ependymomas.
    • Investigating SRS in initial ependymoma treatment could minimize local failures post-surgery.