Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alkaloids from Ruta montana.

D Touati1, Atta-ur-Rahman, A Ulubelen

  • 1Laboratory of Pharmacognosy, Faculty of Medicine and Pharmacy, Rabat, Morocco.

Phytochemistry
|February 19, 2000
PubMed
Summary

Researchers isolated six alkaloids, including four new compounds, from the Ruta montana plant. These findings expand the known chemical diversity of quinoline and 4-quinolone alkaloids.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glycoprotein Hydrogen-Bonding Hypothesis and Its Relationship with Other Mechanisms of Molecular Memory.

Current medicinal chemistry·2026
Same author

Late-Onset Diagnosis of Tuberous Sclerosis Complex Revealed by Renal Angiomyolipoma: A Case Report.

Clinical case reports·2026
Same author

Quantum Consciousness: A Molecular Perspective Involving Glycoprotein-Tunnelling Hypothesis (GPTH).

Current medicinal chemistry·2026
Same author

A Unified Model of Consciousness: Glycoprotein Patterns in Memory Processes and Quantum Entanglement.

Current medicinal chemistry·2025
Same author

Moderate factor XI deficiency and neuraxial procedures in an obstetric cohort: a retrospective study (2014-2021).

International journal of obstetric anesthesia·2024
Same author

Biochemical and <i>In Silico</i> Studies on Triazole Derivatives as Tyrosinase Inhibitors: Potential Treatment of Hyperpigmentation Related Skin Disorders.

Medicinal chemistry (Shariqah (United Arab Emirates))·2024

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Background:

  • Ruta montana is a plant species known to produce various alkaloids.
  • Alkaloids are a diverse group of naturally occurring organic compounds that contain basic nitrogen atoms.
  • Quinoline and 4-quinolone alkaloids exhibit a wide range of biological activities.

Purpose of the Study:

  • To isolate and characterize alkaloids from Ruta montana collected in Rommani, Morocco.
  • To identify known and discover new quinoline and 4-quinolone derivatives.
  • To elucidate the structures of newly identified compounds.

Main Methods:

  • Phytochemical investigation of Ruta montana.
  • Isolation of alkaloid compounds using chromatographic techniques.
  • Structure elucidation employing 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy (HMQC, HMBC) and Mass Spectrometry (MS).

Main Results:

  • Two known alkaloids, 1-methyl-4-methoxy-2-quinolone and evolitrine, were identified.
  • Four new quinoline and 4-quinolone alkaloids were isolated and characterized.
  • The structures of the new compounds were determined as 2-(nonan-8-one)-(1H)-4-quinolone, 2-(nonan-8-one)-4-methoxy-quinoline, 2-(nonan-8-one)-N-methyl-4-quinolone, and 2-(decan-9-one)-N-methyl-4-quinolone.

Conclusions:

  • The study successfully identified known and discovered novel quinoline and 4-quinolone alkaloids from Ruta montana.
  • The structural characterization was confirmed through comprehensive spectroscopic analyses.
  • This research contributes to the understanding of the phytochemical profile of Ruta montana and the diversity of quinoline alkaloids.

Related Experiment Videos