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Cortical reorganization after acute unilateral hearing loss traced by fMRI
D Bilecen1, E Seifritz, E W Radü
1Department of Radiology, University of Basel, Switzerland.
Neurology
|February 19, 2000
Abstract:
Unilateral acoustic stimulation produces a functional MRI (fMRI)-blood-oxygenation-level-dependent (BOLD) response mainly in the contralateral auditory cortex. In unilateral deaf patients, the BOLD response is bilateral. We studied a subject with sudden hearing loss after cochlear nerve resection before and repeatedly after surgery. During normal bilateral hearing, contralateral cortical BOLD responses were found. Progressing compensatory reorganization with bilateral representation of unilateral stimulation was detected over a period of approximately 1 year.