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Updated: Oct 17, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Treatment and pain relief of ulcerative hemangiomas with a polyurethane film
A P Oranje1, F B de Waard-van der Spek, A C Devillers
1Department of Dermato-Venereology, University Hospital Rotterdam and Erasmus University Rotterdam, The Netherlands.
Background:
Hemangiomas are the most common tumors occurring in young children. The most common complication in the growing phase of hemangioma is ulceration.
Aim And Method:
We report healing, pain relief and evolutive effects of a polyurethane film in 8 cases with ulcerative hemangiomas.
Results:
In all 8 infants, prompt pain relief and healing within 1-2 months were observed. An increased regression was also noted within 2-4 months, when the hemangiomas were in the normal proliferative phase.
Conclusion:
As far as the authors know, there is no explanation for the effectiveness of polyurethane film. Explanations could be the occlusive effects of the film inhibiting proliferation or the decrease in blood flow. As primary initial therapeutic approach in ulcerative hemangiomas, we advocate the application of a polyurethane film. This therapy is painless and suitable for children.
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