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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Gamma Knife radiosurgery for pituitary adenomas
1Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Tokyo, Japan. mhayashi@rr.iij4u.or.jp
Stereotactic and Functional Neurosurgery
|February 22, 2000
Summary
Radiosurgery effectively controlled pituitary adenoma growth in 92% of patients. Significant hormone reduction was observed in 75.6%, with a 26.7% normalization rate for endocrinopathy, and a low complication rate of 4.7%.
Area of Science:
- Neurosurgery
- Endocrinology
- Radiation Oncology
Background:
- Pituitary adenomas are common tumors affecting hormone regulation.
- Effective treatment strategies are crucial for managing tumor growth and hormonal imbalances.
Purpose of the Study:
- To evaluate the efficacy and safety of radiosurgery for pituitary adenomas.
- To assess tumor growth control, hormone production normalization, and complication rates.
Main Methods:
- Retrospective analysis of 63 patients with pituitary adenomas treated with radiosurgery over 5 years.
- Dose delivered: mean marginal dose of 22.5 Gy.
- Follow-up exceeding 6 months.
Main Results:
- Tumor growth control achieved in 92% of patients.
- Significant decrease in excessive hormone production in 75.6% of patients with functioning adenomas.
- Endocrinopathy normalization rate was 26.7%.
- Post-radiosurgical complications occurred in 4.7% of patients.
Conclusions:
- Radiosurgery is an effective and safe treatment for pituitary adenomas.
- It demonstrates high rates of tumor growth control and significant hormonal normalization.
- Low complication rates support its use in managing pituitary adenomas.
