[Prospective study on the correlation factors of fetal macrosomia]

The increase of body weight in pregnancy women, 50 g oral glucose challenge test (50 g GCT), pregnant women and umbilicus vein blood insulin (INS), growth hormone (GH), glucose and neonate weight were measured in 110 pregnant women and their neonates were measured to explore the correlation factors of fetal macrosomia. The incidence of macrosomia was higher in pregnant women whose increased weight > or = 15 kg than those < 15 kg. 50 g GCT plasma glucose showed positive correlation with neonatal weight. Which was higher in the group of the fetal macrosomia than of the normal neonates. The results suggest that both the increasing weight of the pregnant women and the 50 g GCT are related parameters to predict fetal macrosomia. To prevent fetal macrosomia the diet should be limited in those who have had a high increasing body weight in pregnancy and appropriate intervention is required to those whose 50 g GCT are positive.