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[Detection of human papillomavirus infection in cervical Pap smears by computer-assisted cytologic test]
Objective:
The sensitivity and accuracy of cytologic computer-assisted test (CCT) in diagnosis of human papillomavirus (HPV) infection in cervical Pap smear were evaluated.
Methods:
Cervical Pap smears obtained from 158 patients with vulva condyloma acuminata were examined by CCT. The diagnostic criteria were based on The Bethesda System (TBS). Simultaneously HPV DNA in cervical mucus was examined by polymerase chain reaction (PCR) technique and cervical biopsy taken under the guidance of colposcopy for pathological examination.
Results:
The sensitivity and accuracy of CCT in diagnosis of cervical HPV infection were 74.62% and 67.72% compared with pathological results whereas 69.11% and 70.88% compared with PCR results respectively.
Conclusion:
The results indicates that CCT, a cytologic pathological technique, is a useful method in diagnosis of clinical and subclinical cervical HPV infection.