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Updated: Aug 11, 2026

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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
[Effects of opium peptide system on the temperature regulation of mice under dry-hot environment with different
Wei Sheng Yan Jiu = Journal of Hygiene Research
|February 22, 2000
Abstract:
The Kunming mice were selected as subjects. Animals were allowed to move and drink freely. The Naloxone(0.02 mg/g) was injected by abdominal cavity. The ability to body temperature stable by mice under the environment with high temperature (41 degrees C, 43 degrees C) was observed. The results showed that after obstructing opium receptor by Naloxone, the ability mentioned above was reduced obviously.

