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Bilateral blindness as the initial presentation of lymphoma of the sphenoid sinus
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Florida, USA.
Purpose:
To report a patient with large-cell lymphoma of the sphenoid sinus presenting with bilateral blindness and no other signs or symptoms.
Method:
Case report. A previously healthy 5-year-old boy complained of sudden vision loss without other systemic complaints.
Results:
Ophthalmologic examination revealed no light perception bilaterally. The pupils of the patient were fixed at 8 mm without reaction to the brightest light stimulus. Systemic examination was unremarkable, and neuroimaging revealed a large sphenoid tumor extending intracranially. Biopsy of the tumor proved to be large-cell lymphoma.
Conclusion:
Large-cell lymphoma affecting children may present initially with blindness, without other systemic symptoms.
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