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Tau protein function in axonal formation
G Paglini1, L Peris, F Mascotti
1Instituto Investigacion Medica Mercedes y Martin Ferreyra (INIMEC-CONICET), Cordoba, Argentina.
Neurochemical Research
|February 24, 2000
Abstract:
Tau protein is a predominantly neuronal microtubule-associated protein that is enriched in axons and is capable of promoting microtubule assembly and stabilization. In the present article we review some of the key experiments directed to obtain insights about tau protein function in developing neurons. Aspects related to whether or not tau has essential, unique, or complementary functions during axonal formation are discussed.