Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Trained discrimination of temporal patterns: cochlear implants in gerbils.

A Kadner1, H Scheich

  • 1Leibniz Institute for Neurobiology, Magdeburg, Germany. Kadner@ifn-magdeburg.de

Audiology & Neuro-Otology
|February 25, 2000
PubMed
Summary

This study developed an animal model to test temporal order cues in cochlear implants. Naive gerbils learned to discriminate electrical pulse trains, but those with prior acoustic experience did not, suggesting pre-existing auditory training can interfere.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of induction therapy in pediatric heart transplant recipients in Switzerland - Analysis of the Swiss national database.

Transplant immunology·2021
Same author

Comparing brain activity patterns during spontaneous exploratory and cue-instructed learning using single photon-emission computed tomography (SPECT) imaging of regional cerebral blood flow in freely behaving rats.

Brain structure & function·2018
Same author

Free left ventricular wall rupter in a newborn.

Images in paediatric cardiology·2016
Same author

Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death.

Neurobiology of disease·2013
Same author

Neuronal and behavioral discrimination between upward and downward pulse interval modulation in cochlea implanted gerbils.

Restorative neurology and neuroscience·2012
Same author

Estimation of the spatiotemporal structure of event-related desynchronization and synchronization in magnetoencephalography.

Journal of neuroscience methods·2012

Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Biomedical Engineering

Background:

  • Cochlear implants (CIs) aim to restore hearing by electrically stimulating the auditory nerve.
  • Understanding how temporal cues are processed is crucial for improving CI efficacy.
  • Developing animal models is essential for investigating CI signal processing.

Purpose of the Study:

  • To establish a gerbil model for discriminating temporal order in electrical cochlear stimulation.
  • To investigate the influence of prior acoustic experience on the discrimination of temporal cues via CIs.

Main Methods:

  • Gerbils were deafened and received a cochlear implant with a single electrode.
  • Animals were trained using a two-way active avoidance shuttle box paradigm.

Related Experiment Videos

  • Two groups were used: naive animals and animals with prior acoustic training.

    • Main Results:

    • Naive animals demonstrated significant discrimination of interval-modulated pulse trains.
    • Animals with prior acoustic experience showed no significant discrimination performance.
    • Discrimination performance was assessed over a 6-day training period.

    Conclusions:

    • Temporal order cues in electrical pulse trains can convey behaviorally relevant information for CIs.
    • Prior auditory experience may conflict with learning temporal order cues through cochlear implants.
    • This model provides insights into optimizing CI signal processing and rehabilitation strategies.