Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The human T cell receptor beta variable (TRBV) genes.

G Folch1, M P Lefranc

  • 1Laboratoire d'ImmunoGénétique Moléculaire, CNRS, Université Montpellier II, Montpellier, France.

Experimental and Clinical Immunogenetics
|February 25, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Specific recognition of a tetrahedral phosphonamidate transition state analogue group by a recombinant antibody Fab fragment.

Amino acids·2013
Same author

T cell diversity and TcR repertoires in teleost fish.

Fish & shellfish immunology·2010
Same authorSame journal

Nomenclature of the human immunoglobulin lambda (IGL) genes.

Experimental and clinical immunogenetics·2002
Same authorSame journal

Nomenclature and overview of the mouse (Mus musculus and Mus sp.) immunoglobulin kappa (IGK) genes.

Experimental and clinical immunogenetics·2002
Same author

DNA sequence variability of IGHG3 alleles associated to the main G3m haplotypes in human populations.

European journal of human genetics : EJHG·2002
Same author

Nomenclature of the human immunoglobulin kappa (IGK) genes.

Experimental and clinical immunogenetics·2001

This report details the Human T Cell Receptor Beta Variable (TRBV) genes, providing comprehensive tables on their repertoire, location, and alleles. It updates the IMGT database with crucial genetic information for immunogenetics research.

Area of Science:

  • Immunogenetics
  • Genomics
  • Molecular Biology

Background:

  • The Human T Cell Receptor Beta Variable (TRBV) genes are critical components of the adaptive immune system.
  • Accurate cataloging of these genes is essential for understanding immune diversity and function.

Purpose of the Study:

  • To present the seventh report of the 'IMGT Locus on Focus' section, specifically detailing human TRBV genes.
  • To provide updated and comprehensive data on the human TRBV gene repertoire, including germline genes, orphons, and alleles.

Main Methods:

  • Compilation and presentation of data in four distinct tables.
  • Leveraging the IMGT (the international ImMunoGeneTics database) as the primary data source.
  • Data organized by gene location (chromosome 7q35 and 9p21) and allelic variations.

Related Experiment Videos

Main Results:

  • Table 1: Quantifies human germline TRBV genes at 7q35 and their potential repertoire.
  • Table 2: Lists human germline TRBV genes located at 7q35.
  • Table 3: Identifies human TRBV orphons on chromosome 9 (9p21).
  • Table 4: Presents a comprehensive human TRBV allele table.

Conclusions:

  • The report consolidates essential information on human TRBV genes, enhancing the IMGT database.
  • This data serves as a valuable resource for researchers in immunogenetics, genomics, and related fields.
  • The organized data facilitates further studies on T cell receptor diversity and immune responses.