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11:15
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
Atypical chronic myeloid leukemia with der(20)t(17;20)(q21;q13)
1Department of Pathology, University of Hong Kong, Queen Mary Hospital, People's Republic of China.
Cancer Genetics and Cytogenetics
|February 25, 2000
Abstract:
We present a case of atypical chronic myeloid leukemia that developed blastic transformation four months after initial presentation, with the blast cells showing multilineage antigen expression. A novel karyotypic abnormality, der(20)t(17;20)(q21;q13), was found in bone marrow cells at diagnosis. The potential role of such an aberration in leukemogenesis is discussed.
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