[Structural and functional changes to the lungs and the lipid metabolic status in cardiogenic shock]

The functional and structural manifestations of lipid metabolism disorders in the lungs were studied in comparison with the changes of fatty acid composition of lipids of pulmonary tissue, venous and arterial blood, expirated air condensate and sweat during the development of cardiogenic shock in patients with myocardial infarction. It has been established that the lungs accumulate neutral lipids and lose phospholipids and polyunsaturated fatty acids. These changes are combined with intracellular lesion of osmiophilic lamellated corpuscles and disturbance of their excretion into alveolar cavities. At the same time the increase of polyunsaturated fatty acids content in expirated air condensate and sweat of patients is noted can be related to the elimination of the excess of these substrates from intercellular space.