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[Celiac disease and lymphoma].
F Balli1, A R Di Biase, P Bertolani
1Dipartimento di Scienze Ostetriche e Ginecologiche e Pediatriche, Università di Modena e Reggio Emilia, Italia.
La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|February 25, 2000
Summary
This study investigated celiac disease (CD) in non-Hodgkin's lymphoma (NHL) patients. One patient with NHL also had celiac disease, suggesting a potential link that requires further research.
Area of Science:
- Gastroenterology and Oncology
- Immunology
Context:
- Celiac disease (CD) is linked to secondary autoimmune and neoplastic conditions.
- The prevalence of CD in non-Hodgkin's lymphoma (NHL) patients is not well-established.
Purpose:
- To investigate the association between celiac disease and non-Hodgkin's lymphoma.
- To screen NHL patients for celiac disease markers before initiating cancer treatment.
Summary:
- Eighty-six patients diagnosed with NHL were tested for antigliadin (AGA) and antiendomysium (EMA) antibodies.
- One patient tested positive for both AGA IgA and EMA, indicating celiac disease.
- No IgA deficiency was observed in the study cohort.
Impact:
- The findings suggest celiac disease may not be uncommon in non-Hodgkin's lymphoma patients.
- Further multi-center studies are needed to statistically confirm the association between CD and lymphomas.
- Early identification of CD in NHL patients could inform clinical management and prognosis.