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Cyclophosphamide therapy and interstitial pulmonary fibrosis
Cancer
|October 1, 1976
Summary
Cyclophosphamide therapy caused interstitial pneumonia and pulmonary fibrosis in a 72-year-old man. Discontinuation of cyclophosphamide led to complete resolution of respiratory symptoms and lung infiltrates.
Area of Science:
- Oncology
- Pulmonology
- Toxicology
Background:
- Cyclophosphamide is a widely used chemotherapy agent.
- Drug-induced lung injury is a known but infrequent complication of chemotherapy.
- Identifying specific chemotherapeutic agents responsible for pulmonary toxicity is crucial for patient management.