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Published on: March 14, 2013
Energy expenditure in the extremely low-birth weight infant
1Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA. cleitch@iupui.edu
Insights
Energy needs for extremely low-birth weight infants are not well-defined due to limited data on intake and expenditure variability. Current estimates suggest requirements likely exceed those of very low-birth weight infants.
Area of Science:
- Neonatal nutrition
- Pediatric metabolism
Background:
- Survival rates for extremely low-birth weight (ELBW) infants are improving.
- Accurate data on the energy requirements of ELBW infants is limited.
- Metabolizable energy intake is approximately 87% of caloric intake.
Purpose of the Study:
- To review current knowledge on energy requirements in ELBW infants.
- To highlight the variability and lack of established recommendations.
Main Methods:
- Review of existing literature on energy balance and expenditure in premature infants.
- Analysis of factors influencing energy intake and expenditure.
Main Results:
- Energy expenditure increases with postnatal age in premature infants.
- Significant variability exists in energy requirements due to multiple influencing factors.
- No definitive recommendations for optimal energy requirements can be made.
Conclusions:
- Optimal energy requirements for ELBW infants remain undetermined.
- ELBW infant energy needs likely surpass those of very low-birth weight infants (105-135 kcal/kg/day).
Abstract:
Information about energy requirements of extremely low-birth weight infants is sparse, despite the rapidly improving survival rates of this population. Metabolizable energy intake can be estimated from energy balance studies and the percentage of caloric intake that is actually absorbed by these infants is approximately 87%. Data on energy expenditure in extremely premature infants is limited; however, energy expenditure has been shown to increase with postnatal age. Because both intake and expenditure are affected by multiple factors, there is significant variability in estimates of the energy requirements in extremely low-birth weight infants. At present, no valid recommendations can be made regarding optimal energy requirements for the extremely low-birth weight infant, except that their requirements probably exceed those of stable, growing very low-birth weight infants, currently estimated at 105 to 135 kcal.kg-1d-1.
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