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Personality disorders and depression: comorbidity.

R M Hirschfeld1

  • 1Department of Psychiatry and Behavioral Sciences, University of Texas-Medical Branch, Galveston 77555-0188, USA.

Depression and Anxiety
|February 26, 2000
PubMed
Summary
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Depression and personality disorders interact in complex ways, but treating depression can improve personality disorder symptoms. Comorbid personality disorders typically do not hinder depression treatment outcomes.

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Depression and personality disorders frequently co-occur.
  • The relationship between depression and personality disorders is bidirectional.
  • Depressive personality disorder represents an interface between the two conditions.

Purpose of the Study:

  • To review the comorbidity of depression, especially chronic depression, with personality disorders.
  • To examine the impact of comorbid personality disorders on depression treatment.
  • To assess the effect of depression treatment on personality disorders.

Main Methods:

  • Literature review of existing data on depression and personality disorder comorbidity.
  • Analysis of studies investigating treatment interactions.
  • Synthesis of findings on treatment efficacy and outcomes.

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Main Results:

  • Comorbid personality disorders generally do not impede the treatment of depression.
  • Successful treatment for depression is linked to improvements in personality disorder symptoms.
  • The three distinct pathways of interaction (vulnerability, precipitation, interface) are supported by data.

Conclusions:

  • Treating depression is crucial and can positively influence comorbid personality disorders.
  • Understanding the interplay between depression and personality disorders informs clinical practice.
  • Further research into specific treatment strategies for comorbid conditions is warranted.