Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ovarian stimulation and endometrial receptivity.

D Valbuena1, M Jasper, J Remohí

  • 1Instituto Valenciano de Infertilidad, Valencia, Spain.

Human Reproduction (Oxford, England)
|February 26, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychosocial and environmental motivational key factors behind the parenthood desire in infertile couples at the time of COVID-19.

Journal of assisted reproduction and genetics·2024
Same author

Severe pulmonary hypertension and circulatory failure associated with Congenital syphilis. Case report.

Journal of neonatal-perinatal medicine·2024
Same author

RISEinFAMILY project: the integration of families at neonatal intensive care units (NICUs) to empower them as primary caregivers: study protocol for a stepped wedge cluster controlled trial.

Trials·2024
Same author

Correction to: The HERA (Hyper‑response Risk Assessment) Delphi consensus for the management of hyper‑responders in in vitro fertilization.

Journal of assisted reproduction and genetics·2023
Same author

The HERA (Hyper-response Risk Assessment) Delphi consensus for the management of hyper-responders in in vitro fertilization.

Journal of assisted reproduction and genetics·2023
Same author

Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expression.

Frontiers in molecular biosciences·2023
Same journal

ESHRE recommendations on Good Practice in the IVF laboratory†.

Human reproduction (Oxford, England)·2026
Same journal

Evidence for de novo synthesis of corticosteroids in the human ovary.

Human reproduction (Oxford, England)·2026
Same journal

Characterizing endometriosis and adenomyosis symptom clusters and their impact on quality of life in the All of Us Research Program.

Human reproduction (Oxford, England)·2026
Same journal

A new regulatory framework: impact of the SoHO Regulation for medically assisted reproduction.

Human reproduction (Oxford, England)·2026
Same journal

Subfertility in relation to gestational weight gain and gestational diabetes: the Norwegian Mother, Father and Child Cohort Study.

Human reproduction (Oxford, England)·2026
Same journal

Pathogenic variants in ACTRT3 lead to male infertility characterized by fertilization defects.

Human reproduction (Oxford, England)·2026
See all related articles

High oestradiol levels negatively impact embryo implantation in in-vitro fertilization (IVF) for high responder patients. A step-down regimen may improve uterine receptivity and IVF success rates.

Area of Science:

  • Reproductive Endocrinology
  • In-Vitro Fertilization
  • Embryo Implantation

Background:

  • Endometrial receptivity is crucial for successful in-vitro fertilization (IVF).
  • High responder patients often experience impaired implantation despite good embryo quality.
  • Elevated oestradiol levels are suspected contributors to implantation failure in this cohort.

Purpose of the Study:

  • To investigate the impact of high oestradiol concentrations on endometrial receptivity in high responder IVF patients.
  • To identify clinical strategies for enhancing uterine receptivity in this specific patient group.

Main Methods:

  • Selection of high responder patients with impaired implantation.
  • Analysis of oestradiol concentrations on the day of human chorionic gonadotrophin (HCG) administration.

Related Experiment Videos

  • Evaluation of clinical outcomes following a step-down regimen.

    • Main Results:

    • High oestradiol concentrations on HCG administration day were found to be detrimental to uterine receptivity.
    • A step-down regimen was proposed as a potential strategy to mitigate these negative effects.

    Conclusions:

    • Managing high oestradiol levels is critical for improving IVF success in high responder patients.
    • Implementing a step-down regimen may enhance endometrial receptivity and implantation rates.