Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perinatal mortality in Type 2 diabetes mellitus.

T Cundy1, G Gamble, K Townend

  • 1Department of Medicine, University of Auckland, New Zealand. t.cundy@auckland.ac.nz

Diabetic Medicine : a Journal of the British Diabetic Association
|February 26, 2000
PubMed
Summary

Perinatal mortality is significantly higher in pregnancies with Type 2 diabetes mellitus (DM) compared to Type 1 DM or gestational diabetes. Maternal obesity and late presentation are key factors contributing to increased late fetal deaths in Type 2 DM pregnancies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Muscle water properties in raw intact broiler breast fillets with the woody breast condition.

Poultry science·2020
Same author

Body composition of New Zealand-born term babies differs by ethnicity, gestational age and sex.

Early human development·2019
Same author

Inaccurate retraction notice for meta-analysis by Iwamoto et al.

Acta neurologica Scandinavica·2018
Same author

Exudate Protein Composition and Meat Tenderness of Broiler Breast Fillets.

Poultry science·2015
Same author

Long-term effectiveness of a community-based model of care in Māori and Pacific patients with type 2 diabetes and chronic kidney disease: a 4-year follow up of the DElay Future End Stage Nephropathy due to Diabetes (DEFEND) study.

Internal medicine journal·2015
Same author

Comparison of the management and in-hospital outcomes of acute coronary syndrome patients in Australia and New Zealand: results from the binational SNAPSHOT acute coronary syndrome 2012 audit.

Internal medicine journal·2015

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Perinatal Medicine

Background:

  • Pregnancies in women with Type 2 diabetes mellitus (DM) are increasing globally, surpassing those with Type 1 DM.
  • Limited published data exist on perinatal mortality rates specifically for Type 2 DM pregnancies.
  • This study addresses this gap by reporting observational data from a population with a high prevalence of Type 2 DM.

Purpose of the Study:

  • To report observational data on perinatal mortality in pregnancies complicated by Type 2 diabetes mellitus.
  • To compare perinatal mortality rates in Type 2 DM with Type 1 DM, gestational diabetes mellitus (GDM), and the general population.
  • To identify factors contributing to perinatal mortality in Type 2 DM.

Main Methods:

  • A 12-year observational study (1985-1997) at a specialized diabetes clinic.

Related Experiment Videos

  • Inclusion of 434 pregnancies with Type 2 DM, 160 with Type 1 DM, and 932 with GDM.
  • Classification of perinatal mortality included intermediate fetal death, late fetal death, and early neonatal death.

    • Main Results:

    • Perinatal mortality in Type 2 DM was 46.1/1,000, significantly higher than general population (12.5), Type 1 DM (12.5), and GDM (8.9) (P < 0.0001).
    • Congenital malformations represented only 10% of perinatal deaths; increased late fetal death (seven-fold) and intermediate fetal/late neonatal death (2.5-fold) were observed.
    • Women with Type 2 DM were older, more obese, and presented later to the clinic compared to those with Type 1 DM.

    Conclusions:

    • Perinatal mortality is significantly elevated in Type 2 DM pregnancies, primarily due to increased late fetal deaths.
    • Maternal obesity and late presentation to care are potential contributors to the high rates of perinatal mortality.
    • Unrecognized Type 2 DM in women diagnosed with GDM poses a high risk, while milder glucose intolerance shows lower perinatal mortality.