[The effect of scopolamine on the spatial organization of rat cortical potentials]

O Kh Koshtoiants¹, T A Korol'kova, S N Kozhechkin

¹Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.

Zhurnal Vysshei Nervnoi Deiatelnosti Imeni I P Pavlova

|February 29, 2000

Abstract:

The influence of scopolamine (1 mg/kg, i.p.) on the spatial organization of the neocortical electrical activity was studied in rats. A decrease in the spectral power and coherence of brain potentials in the range of the dominant theta-rhythm peak (6.00-7.25 Hz) and their increase in the adjacent low-frequency band were observed. Both indices were decreased in the wide beta band (19.00-30.00 Hz). The described changes took place over the whole areas of the right hemisphere and parieto-temporal region of the left hemisphere. The obtained results are discussed with respect to the role of the cholinergic brain system in the higher nervous activity.

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Abstract:

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