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Related Experiment Videos

Augmented amputations of the lower extremity.

D G Mohler1, J I Kessler, B E Earp

  • 1Division of Orthopaedics, Stanford University Medical School, CA, USA.

Clinical Orthopaedics and Related Research
|February 29, 2000
PubMed
Summary
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Bone grafting using allografts or autografts can create a better residual limb after lower extremity amputation for sarcoma. This technique improved bone length and prosthesis fitting for patients.

Area of Science:

  • Orthopedic Surgery
  • Surgical Oncology
  • Biomaterials Science

Background:

  • High-grade sarcomas often necessitate lower extremity amputation.
  • Traditional amputation techniques can result in suboptimal residual limbs, impacting prosthesis fitting and function.
  • Bone augmentation offers a potential solution to improve residual limb length and quality.

Purpose of the Study:

  • To evaluate the efficacy of bone augmentation using allografts or autografts in patients undergoing lower extremity amputation for sarcoma.
  • To assess the impact of augmentation on residual limb length, wound healing, graft survival, and functional outcomes.
  • To determine if bone augmentation can prevent more proximal amputations.

Main Methods:

  • Retrospective review of ten patients who underwent lower extremity amputation for high-grade sarcomas.

Related Experiment Videos

  • Bone augmentation performed using nonvascularized structural allografts or autografts.
  • Follow-up averaged 54 months, assessing graft union, wound complications, infection, recurrence, bone length changes, and prosthesis use.

    • Main Results:

    • No graft nonunions were observed.
    • Bone augmentation achieved a 42% average increase in bone length when performed for length.
    • All patients successfully used standard prostheses.
    • Half of the patients avoided more proximal amputations due to augmentation.
    • Complications included three wound problems, one graft resorption, one late infection, and one local recurrence.

    Conclusions:

    • Nonvascularized structural allografts and autografts are effective for bone augmentation in lower extremity amputations.
    • This technique can create a superior residual limb, improving function and prosthesis fit.
    • Bone augmentation should be considered to optimize outcomes in select amputation cases.