Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nail alterations secondary to pactitaxel [corrected] therapy.

M Almagro1, J D Pozo, J Garcia

  • 1Departments of Dermatology and Family Medicine, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 La Coruña, Spain. Almagro@canalejo.org

European Journal of Dermatology : EJD
|February 29, 2000
PubMed
Summary

Paclitaxel, a taxane drug, can cause nail changes like onycholysis and discoloration. These nail alterations are rarely reported with paclitaxel but are more common with docetaxel.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Steps towards seizure freedom with the use of Cenobamate.

Epilepsy & behavior : E&B·2025
Same author

Phylogenetic characterization of Bifidobacterium kimbladii sp. nov., a novel species from the honey stomach of the honeybee Apis mellifera.

Systematic and applied microbiology·2025
Same author

Inspiring healthcare transformation toward a sustainable, low-carbon future: A growing discipline.

Radiography (London, England : 1995)·2024
Same author

A survey of the effectiveness of centralized consilia in providing advice on drug-resistant TB.

IJTLD open·2024
Same author

Early focal electroencephalogram and neuroimaging findings predict epilepsy development after aneurysmal subarachnoid hemorrhage.

Epilepsy & behavior : E&B·2024
Same author

[Risk of epilepsy after a first epileptic seizure with unknown etiology in elderly patients].

Revista de neurologia·2024

Area of Science:

  • Oncology
  • Dermatology

Background:

  • Taxanes, including docetaxel and paclitaxel, are crucial in cancer chemotherapy.
  • Nail alterations are a known side effect of docetaxel therapy.

Observation:

  • This report details two cases of nail changes observed in patients undergoing paclitaxel therapy.
  • The observed nail alterations included onycholysis and nail discoloration.

Findings:

  • Nail alterations, specifically onycholysis and discoloration, are associated with paclitaxel treatment.
  • These side effects appear to be less frequent with paclitaxel compared to docetaxel.

Implications:

  • Clinicians should be aware of potential nail side effects from paclitaxel chemotherapy.
  • Further research is warranted to understand the incidence and mechanisms of paclitaxel-induced nail changes.

Related Experiment Videos