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Bacteriological analysis of burn sepsis
B S Nagoba1, S R Deshmukh, B J Wadher
1Microbiology Dept, M.I.M.S.R. Medical College, Latur.
Indian Journal of Medical Sciences
|March 1, 2000
Summary
Burn sepsis infections commonly involve opportunistic bacteria like Pseudomonas aeruginosa and Staphylococcus aureus. Ciprofloxacin showed effectiveness, but increasing bacterial resistance is a significant concern.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Burn wound infections are a significant cause of morbidity and mortality.
- Opportunistic bacteria frequently cause burn sepsis, leading to complications.
- Understanding the prevalent pathogens and their antimicrobial susceptibility is crucial for effective treatment.
Purpose of the Study:
- To identify the spectrum of opportunistic bacteria isolated from burn sepsis cases.
- To determine the prevalence of monobacterial versus polybacterial infections.
- To evaluate the in vitro efficacy of common antibacterial agents against these isolates.
Main Methods:
- Bacterial isolation and identification from 65 burn sepsis patient swabs.
- Antimicrobial susceptibility testing of isolated bacterial strains.
- Analysis of infection types (monobacterial vs. polybacterial) and predominant pathogens.
Main Results:
- 114 opportunistic bacteria were isolated, with Pseudomonas aeruginosa (53.8%) and Staphylococcus aureus (38.4%) being the most common.
- Polybacterial infections (61.5%) were more frequent than monobacterial infections (38.4%).
- Ciprofloxacin (42.9%) demonstrated the highest efficacy, yet overall resistance rates were notably high and increasing.
Conclusions:
- Pseudomonas aeruginosa is the predominant pathogen in burn sepsis, often in polymicrobial settings.
- Increasing antimicrobial resistance poses a significant challenge in managing burn sepsis.
- Continuous monitoring of bacterial susceptibility patterns is essential for guiding empirical therapy.