Suppressor cells in demyelinating disease: a new paradigm for the new millennium
1Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI 48201, USA. rswanbo@med.wayne.edu
Journal of Neuroimmunology
|March 1, 2000
Abstract:
This brief review highlights investigations conducted over the past three decades concerning the role of suppressor T cells in the regulation of experimental autoimmune encephalomyelitis (EAE). In addition, more recent studies are summarized which suggest that apoptosis of autoreactive T cells is also involved in the regulation of EAE. The possibility that natural killer (NK) cells mediate apoptosis is also considered.
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