Erythema multiforme after application of aural Gentisone HC drops

Area of Science:

• Dermatology
• Otolaryngology
• Pediatrics

Background:

• Erythema multiforme is an uncommon, acute, self-limiting mucocutaneous condition.
• It presents with lesions of varying severity and recurrence patterns.

Observation:

• A four-year-old girl developed erythema multiforme.
• The condition was secondary to topical aural application of Gentisone HC drops (hydrocortisone acetate/gentamicin).
• This was prescribed for otorrhoea following grommet insertion.

Findings:

• This is the first reported case of erythema multiforme secondary to a topical aminoglycoside/steroid preparation.
• The clinical features of this case are described.
• The relevant literature was reviewed.

Implications:

• This case expands the known triggers for erythema multiforme.
• It highlights the importance of considering topical medications as potential causative agents.
• Awareness among clinicians is crucial for accurate diagnosis and management.