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Related Experiment Videos

Confluent choroidal infiltrates with sarcoidosis.

B E Cook1, D M Robertson

  • 1Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Retina (Philadelphia, Pa.)
|March 4, 2000
PubMed
Summary
This summary is machine-generated.

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Confluent plaquelike choroidal infiltrates, a rare sign of sarcoidosis, can appear with minimal inflammation. These lesions often radiate from the optic nerve and respond well to corticosteroid treatment.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Systemic Inflammatory Diseases

Background:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Ocular involvement in sarcoidosis can manifest in various ways.
  • Choroidal infiltrates are a less common presentation of ocular sarcoidosis.

Observation:

  • Four patients with systemic sarcoidosis presented with unique confluent, plaquelike choroidal infiltrates.
  • These infiltrates were yellowish, thickened, and radiated from the optic nerve in an ameboid pattern.
  • Patients experienced mild vision blurring; other typical sarcoid uveitis signs were notably absent.

Findings:

  • Fluorescein angiography showed early hypofluorescence with progressive hyperfluorescence and late staining of active lesions.

Related Experiment Videos

  • Treatment with corticosteroids led to vision improvement and lesion resolution.
  • Spontaneous resolution occurred in some lesions, leading to chorioretinal atrophy.

    • Implications:

    • Plaquelike choroidal infiltrates can be an isolated ocular finding in sarcoidosis.
    • This presentation may be the initial sign of systemic sarcoidosis.
    • Prompt recognition and treatment with corticosteroids are crucial for visual outcomes.