Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Premedication, preparation, and surveillance.

G D Bell1

  • 1Faculty of Medical Sciences, University of Sunderland, United Kingdom. duncan_bell@compuserve.com

Endoscopy
|March 4, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The tracheal system of the Common Wasp (Vespula vulgaris) - A micro-CT study.

Journal of insect physiology·2023
Same author

Visualising fat reserves in an insect: A method using X-ray micro-computerised tomography of the Common Wasp (Vespula vulgaris).

Zoology (Jena, Germany)·2023
Same author

Three-dimensional rendering of otolith growth using phase contrast synchrotron tomography.

Journal of fish biology·2016
Same author

Sports Medicine: What family physicians see and what they need to learn.

Canadian family physician Medecin de famille canadien·2011
Same author

Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation.

The international journal of medical robotics + computer assisted surgery : MRCAS·2007
Same author

Long-term study of re-infection following successful eradication of Helicobacter pylori infection.

Alimentary pharmacology & therapeutics·2006
Same journal

Correction: A novel technique for endoscopic stepwise clamping and resection of giant pedunculated colonic polyps.

Endoscopy·2026
Same journal

Feasibility and safety of an adaptive endoscopic resection algorithm guided by the muscle-retracting sign for early rectal cancer.

Endoscopy·2026
Same journal

Is ERCP losing its dominance to endoscopic ultrasound-guided biliary drainage for malignant distal biliary obstruction?

Endoscopy·2026
Same journal

Endoscopic ultrasound-guided gallbladder drainage for distal malignant biliary obstruction: It's not the tool - but knowing which one to use!

Endoscopy·2026
Same journal

Endoscopic closure of a large gastric mucosal defect using a novel endoscopic suturing device in a porcine model.

Endoscopy·2026
Same journal

Anchor clip-assisted detachable loop ligation for definitive hemostasis and closure of a high-risk bleeding gastric ulcer.

Endoscopy·2026
See all related articles

This review highlights variations in IV sedation for colonoscopy, discussing Propofol, midazolam, and diazepam. It also covers hydrogen peroxide for bleeding lesions and antispasmodics like hyoscyamine sulphate, cautioning about side effects and hypoxemia risks.

Area of Science:

  • Gastroenterology and Anesthesiology
  • Clinical Practice Guidelines
  • Patient Safety

Background:

  • Significant international variation exists in intravenous (IV) sedation practices for endoscopic procedures.
  • The debate on sedation versus no sedation continues, particularly for colonoscopy.
  • Propofol, midazolam, diazepam, and flumazenil are frequently discussed agents in procedural sedation.

Purpose of the Study:

  • To review current literature on IV sedation practices for colonoscopy.
  • To evaluate the efficacy and safety of various agents and adjuncts used in gastrointestinal endoscopy.
  • To address patient safety concerns, including informed consent and management of adverse events like hypoxemia.

Main Methods:

  • Review of recent studies on Propofol, midazolam, and diazepam for procedural sedation.

Related Experiment Videos

  • Analysis of papers discussing the use of 3% hydrogen peroxide for visualizing gastro-duodenal lesions.
  • Evaluation of studies on antispasmodics, specifically hyoscyamine sulphate, for colonoscopy assistance.
  • Review of data on hypoxemia incidence during gastroscopy, colonoscopy, and ERCP.

    • Main Results:

    • Propofol use necessitates anesthesiologist involvement due to its anesthetic properties.
    • Hyoscyamine sulphate may shorten caecal intubation times and improve sedation but can cause tachycardia.
    • Hypoxemia remains a concern during procedures, with incidences often falling below acceptable anesthetic standards.
    • Supplemental oxygen use could significantly mitigate risks associated with desaturation.

    Conclusions:

    • Careful consideration of sedation agents and practices is crucial for patient safety during endoscopic procedures.
    • The use of hyoscyamine sulphate requires further clarification regarding its safety profile, particularly tachycardia.
    • Routine monitoring and management of oxygen saturation, including supplemental oxygen, are essential to prevent dangerous hypoxemia during gastroscopy, colonoscopy, and ERCP.