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Related Experiment Videos

Association between watershed zone and visual field defect in normal tension glaucoma.

Y Sato1, G Tomita, E Onda

  • 1Department of Ophthalmology, Gifu University School of Medicine, Gifu-ken, Japan.

Japanese Journal of Ophthalmology
|March 4, 2000
PubMed
Summary
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The location of the watershed zone, a vascular watershed, significantly impacts optic nerve head damage in normal tension glaucoma (NTG). Watershed zones involving more of the optic nerve head correlate with greater visual field defects in NTG patients.

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Neuro-ophthalmology

Background:

  • Normal tension glaucoma (NTG) is characterized by optic nerve damage without elevated intraocular pressure.
  • The role of vascular factors, such as watershed zones, in NTG pathogenesis is increasingly recognized.
  • Understanding the relationship between vascular anatomy and glaucomatous damage is crucial for early diagnosis and treatment.

Purpose of the Study:

  • To investigate the association between the location of the watershed zone and glaucomatous optic nerve head (ONH) damage in patients with NTG.
  • To determine if the extent to which the watershed zone involves the ONH correlates with the severity of visual field defects.

Main Methods:

  • Indocyanine green fluorescence angiography was utilized in 54 eyes of 27 patients diagnosed with NTG.

Related Experiment Videos

  • A scanning laser ophthalmoscope was employed to visualize and analyze the watershed zones in relation to the optic nerve head.
  • Patients were categorized based on whether the watershed zone excluded, partially included, or fully included the ONH.

    • Main Results:

    • A watershed zone not including the ONH was observed in 14.8% of eyes.
    • The watershed zone partially included the ONH in 59.3% of eyes.
    • The watershed zone fully included the ONH in 25.9% of eyes, with 37.0% of patients exhibiting different watershed zone types in each eye.

    Conclusions:

    • A significant correlation exists between the watershed zone's location and the severity of glaucomatous ONH damage.
    • Eyes with watershed zones encompassing a larger portion of the ONH exhibited greater mean visual field deviation.
    • The findings suggest that the anatomical location of the watershed zone is a critical factor influencing the progression of visual field defects in NTG.