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Endogenous opiates: 1998.

A L Vaccarino1, G A Olson, R D Olson

  • 1Department of Psychology, University of New Orleans, LA 70148, USA. avaccari@uno.edu

Peptides
|March 4, 2000
PubMed
Summary
This summary is machine-generated.

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This review covers 1998 research on the behavioral effects of opiate peptides and antagonists, excluding pure analgesia but including stress-induced pain relief. It details impacts on mood, reward, and various physiological functions.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Behavioral Science

Background:

  • The opiate system plays a crucial role in regulating numerous physiological and behavioral processes.
  • Annual reviews are essential for synthesizing the rapidly evolving research in this field.
  • Understanding the behavioral effects of opiates is key to addressing addiction and related disorders.

Purpose of the Study:

  • To provide a comprehensive summary of research published in 1998 on the behavioral effects of opiate peptides and antagonists.
  • To highlight findings related to stress, tolerance, dependence, and various functional systems.
  • To consolidate information on the diverse behavioral impacts of the opiate system.

Main Methods:

  • Systematic review and synthesis of scientific literature published in 1998.

Related Experiment Videos

  • Inclusion of studies on behavioral effects, excluding purely analgesic research, but including stress-induced analgesia.
  • Categorization of findings across multiple behavioral and physiological domains.

    • Main Results:

    • Opiate peptides and antagonists influence a wide range of behaviors, including stress responses, eating, drinking, and locomotion.
    • The opiate system is implicated in mood regulation, learning, memory, and reward processes.
    • Research in 1998 also explored the opiate system's involvement in cardiovascular, respiratory, gastrointestinal, and immunologic functions.

    Conclusions:

    • The opiate system exerts broad behavioral control, extending beyond pain modulation.
    • Continued research is vital for understanding the complex roles of opiate peptides and antagonists in health and disease.
    • The findings underscore the multifaceted nature of opiate system involvement in behavior and physiology.