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Impact of the sequential poliovirus immunization schedule: a demonstration project
M S Kolasa1, S N Desai, K M Bisgard
1National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. mxk2@cdc.gov
American Journal of Preventive Medicine
|March 4, 2000
Summary
Compliance with the sequential inactivated poliovirus vaccine (IPV) schedule was high in a Georgia county. The new schedule did not hinder the delivery of other essential childhood immunizations.
Area of Science:
- Pediatrics
- Immunology
- Public Health
Background:
- The sequential poliovirus immunization schedule, utilizing inactivated poliovirus vaccine (IPV) for initial doses, was implemented to improve polio vaccination compliance.
- Assessing immunization coverage rates before and after this schedule change is crucial for public health strategies.
Purpose of the Study:
- To evaluate adherence to the sequential poliovirus immunization schedule using IPV for the first two doses.
- To assess changes in immunization coverage rates following the schedule implementation in public health clinics.
Main Methods:
- A retrospective analysis of immunization histories from three infant birth cohorts was conducted.
- Cohorts included a baseline group (pre-schedule change), an evaluation group (post-schedule change), and a dose-3 group to assess third dose eligibility.
Main Results:
- Following the schedule change, 94% of infants received IPV for their first poliovirus dose.
- High compliance was observed for other vaccines (DTP/DTaP, Hib, Hepatitis B) administered simultaneously.
- 78% of infants in the dose-3 cohort received a mixed IPV/oral poliovirus vaccine schedule.
Conclusions:
- The sequential IPV schedule demonstrated very high compliance in a low-income, diverse population.
- The implementation of the sequential schedule did not negatively impact the overall delivery of recommended childhood immunizations.